Welcome to the homepage for the Ophthalmic Imaging Research Laboratory (Glaucoma Imaging Group (GIG))! We are part of the Department of Ophthalmology, located in the Eye and Ear Institute at the University of Pittsburgh Medical Center Eye Center. Glaucoma causes a change in the structure of retinal tissue and the optic nerve, and our team of ophthalmologists, engineers, software specialists, statisticians, and trainees assisted by support team specialize in the development and testing of cutting edge ophthalmic imaging devices. These devices can be used to obtain structural information about the optic nerve and surrounding retina. They are being tested for their efficacy in detecting glaucoma and the changes due to glaucomatous progression. Since there is currently no known cure for glaucoma, early detection is the key to slowing down progression. Imaging devices may assist in early detection.

Group Members:
Joel S. Schuman, MD - Chairman, UPMC Eye Center
Gadi Wollstein, MD - Director, Ophthalmic Imaging Research Laboratories
Hiroshi Ishikawa, MD - Director, Ocular Imaging Center
Larry Kagemann, PhD - Co-Director, OVSR Center Imaging Module
Michelle G. Sandrian, PhD - Director, In-vivo Optical Imaging Lab
Richard A. Bilonick, PhD
Yun Ling, PhD
Kristy Truman
Melessa Salay
Rose Carla Aubourg
Michael DeRosa
Katie Lucy

Chieh-Li Chen, MS
Bo Wang, BS
Tigran Kostanyan, MD
Anusha Rangarajan, MS

Founded by Professor Joel S. Schuman, MD, Chairman of the Department of Ophthalmology, Director of UPMC Eye Center and Professor of Bioengineering, the Ophthalmic Imaging Research Laboratory is directed by Gadi Wollstein, MD, an ophthalmologist and scientist specializing in the clinical application of ocular imaging. The research group includes the following members: Hiroshi Ishikawa, MD, an ophthalmologist and scientist specializing in the development of medical imaging algorithms; Larry Kagemann, PhD, a biomedical engineer specializing in ocular structure and function imaging; Michelle G. Sandrian, PhD, a biomedical engineer specializing in multimodal imaging system development; Richard A. Bilonick, PhD, a statistician; Yun Ling, PhD, a biostatistics research specialist; Chieh-Li Chen, MS, a bioengineering graduate student; Bo Wang, BS, an MD/PhD graduate student; Tigran Kostanyan, MD, a visiting scholar from Yerevan State Medical University; Anusha Rangarajan, MS, a bioengineering graduate student. The laboratory also includes ophthalmic imaging technicians, clinical coordinators, and IRB liaisons. The group consistently trains post-doctoral fellows and scientists, residents in ophthalmology, and medical, bioengineering, and biostatistics students.

Research Opportunities

Research Opportunities: Gadi Wollstein, MD, 412-647 0325, wollsteing@upmc.edu


Healthy subjects and subjects with glaucoma or glaucoma suspect are welcome to participate in various glaucoma studies. For further information contact Melessa Salay 412-383 9884.


Laboratory of Ocular Biomechanics, University of Pittsburgh (Ian A. Sigal, PhD; Jonathan Grimm, BS)
Neuroscience Imaging Center and Neuroimaging Laboratory, University of Pittsburgh (Kevin C. Chan, PhD)
Visual Neuroscience Laboratory, University of Pittsburgh (Matthew A. Smith, PhD)
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology (James G. Fujimoto, PhD)
Institute for Human & Machine Cognition in Pensacola (Choh Man Teng)
Department of Ophthalmology, Oregon Health & Science University (David Huang, MD, PhD)
New England Eye Center, Tufts Medical Center (Jay S. Duker, MD; Cynthia Mattox, MD)
College of Computing, Georgia Institute of Technology (James M. Rehg, PhD)
Departments of Neurology, Ophthalmology, and Epidemiology, University of Pennsylvania School of Medicine (Laura J. Balcer, MD, MSCE)
Physical Sciences, Inc. (R. Daniel Ferguson)
The NEIGHBORHOOD Consortium, Massachusetts Eye and Ear (Janey L. Wiggs, MD)
US Food and Drug Administration (Daniel X. Hammer, PhD)
Department of Ophthalmology and Visual Sciences, W. K. Kellogg Eye Center, University of Michigan (Joshua D. Stein, MD, MS)
Department of Ophthalmology, Asan Medical Center, University of Ulsan, College of Medicine, Seoul, Korea (Kyung Rim Sung, MD)
Intel Labs Pittsburgh (Mei Chen, PhD)

Financial Support

National Institute of Health R01-EY013178, R01-EY011289, R01-EY021641, R44-EY018986, P30-EY008098, R01-EY023966.
Eye and Ear Foundation (Pittsburgh, PA)
Research to Prevent Blindness

Last updated on 07/01/2014